Jonas Tegenfeldt

Main expertise: microfluidics, microscopy, ...

Tegenfeldt earned his MSc in Engineering Physics from Uppsala University (1992) and his PhD in Solid State Physics from Lund University (1997). He performed his postdoctoral training in the laboratories of Prof EC Cox and Prof RH Austin at Princeton University 1998-2003 after which he returned to Lund to establish his own group. He has been a Swedish Research Council Research Fellow 2008 to 2014.

Tegenfeldt pioneered the usage of nanochannels for direct visualization of DNA through stretching in confinement[1], electrodeless dielectrophoresis[2]. Further, morphological and deformability based sorting based on deterministic lateral displacement was pioneered in his lab[3, 4] as well as a barcode labeling scheme specifically for DNA analysis based on localized melting[5]. Key patents on DNA analysis essential for startup of two companies: BioNanoGenomics (formerly known as Bionanomatrix), and Pathogenetix (formerly known as USGenomics). He has more than 70 publications including invited review papers and book chapters. His publications have attracted more than 4000 citations resulting in an h-index of 34.

Since 2014 he is a full professor of nanophysics at Lund University, Lund, Sweden.

1. Tegenfeldt, J.O., et al., The dynamics of genomic-length DNA molecules in 100-nm channels. Proceedings of the National Academy of Sciences of the United States of America, 2004. 101(30): p. 10979-10983.
2. Chou, C.-F., et al., Electrodeless Dielectrophoresis of Single- and Double-stranded DNA. The Biophysical Journal, 2002. 83(4): p. 2170-2179.
3. Holm, S.H., et al., Separation of parasites from human blood using deterministic lateral displacement. Lab on a Chip, 2011. 11(7): p. 1326-1332.
4. Beech, J.P., et al., Morphology- and compliance-based separation in deterministic lateral displacement devices.Lab on a Chip, 2012. 12(6): p. 1048-1051.
5. Reisner, W., et al., Single-molecule denaturation mapping of DNA in nanofluidic channels. Proceedings of the National Academy of Sciences, 2010. 107(30): p. 13294-13299.